Should Achievement Tests be Used to Judge School Quality?

Should antihistamines be used to treat anaphylaxis?

Unsurprisingly, a recent comparison of important international guidelines found conflicting advice about antihistamines, reflecting the uncertainty in international clinical practice: a US guideline recommends the use of diphenhydramine as second line treatment in anaphylaxis; evidence for this recommendation is graded as "expert opinion/ extrapolated from higher order evidence. DRUG INFORMATIO...

Videoregistration of surgery should be used as a quality control.

Quality control of medical treatment is strictly organized and supervised. Efficacy and safety have to be proven in large randomized controlled trials, which need ethical review board approval. Content and quality of marketed drugs is controlled by industry and government. After market introduction, postmarketing surveillance is organized. This quality control is necessary to obtain reliable an...

Should levodopa be used anymore?

Levodopa is the most potent dopaminergic oral drug available in clinical practice. After chronic treatment, many patients with Parkinson's disease develop dyskinesia and motor fluctuations which are difficult to manage. It was hoped that introduction of dopaminergic agonists could diminish these side effects while keeping the same efficacy as levodopa. Prospective clinical data do not support t...

Genomic Tests Should be Used to Help Guide Treatment of Prostate Cancer: No.

Comment: How Should Indirect Evidence Be Used?

Indirect evidence is crucial for successful statistical practice. Sometimes, however, it is better used informally. Future efforts should be directed toward understanding better the connection between statistical methods and scientific problems.